产品货号：
Z27644
中文名称：
TAB1抗体
英文名称：
Anti-TAB1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TAB1 Antibody |
| 指标别名 | 3' Tab1;MAP3K7IP1;TAB1;TAK1 binding protein 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | TAB1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | TAB1 antibody was raised against a synthetic peptide corresponding to 13 amino acids in the center of human TAB1.The immunogen is located within amino acids 220 - 270 of TAB1. |
| 计算分子量 | 55kDa |
| 成分 | TAB1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | TAB1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | TAB1 was identified as a regulator of the MAP kinase kinase kinase TAK1/MAP3K7,which is known to mediate various intracellular signaling pathways,such as those induced by TGF-beta and members of the Toll-IL-1R (TIR) superfamily,thus acting as an intermediate in both proliferative and innate and adaptive immune responses.This protein,together with either TAB2 or TAB3,activates TAK1 kinase in response to upstream signals.It has been shown that the C-terminal portion of TAB1 is sufficient for binding and activation of TAK1,while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF-beta,demonstrating how this protein can function as a mediator between TGF-beta receptors and TAK1. |
| Uniprot ID | Q15750 |
| 基因名全称 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1 |
| 蛋白名全称 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1 |
| 推荐稀释比 | TAB1 antibody can be used for the detection of TAB1 by Western blot at 0.5 to 2μg/mL.Antibody can also be used for immunocytochemistry starting at 1μg/mL.For immunofluorescence start at 2μg/mL.Antibody validated:Western Blot in mouse samples;Immunocytochemistry in human samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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